CCNH
cyclin H
Synonyms:
CAK, p34, p37
Species:
Human CCNH (902), Mouse Ccnh (66671), Rat Ccnh (84389), domestic guinea pig Ccnh (100726162), naked mole-rat Ccnh (101714118), sheep CCNH (101104905), Zebrafish ccnh (541325), cow CCNH (615512), Horse CCNH (100065185), domestic cat CCNH (101095398) ...More
UniProtKB ID:
Gene ID:
- Human(902) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
- Mouse(66671) cyclin H
- Rat(84389) cyclin H
- domestic guinea pig(100726162) cyclin H
- naked mole-rat(101714118) cyclin H
- sheep(101104905) cyclin H
- Zebrafish(541325) cyclin H
- cow(615512) cyclin H
- Horse(100065185) cyclin H
- domestic cat(101095398) cyclin H
- dog(479156) cyclin H
- chicken(427328) cyclin H
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CCNH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-CCNH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Cyclin H Antibody, clone 3N5S3, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-Cyclin H (pThr315) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
CDK7/Cyclin H1/MNAT1, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human