CCDC88A
coiled-coil domain containing 88A
Synonyms:
APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212
Species:
Human CCDC88A (55704), Mouse Ccdc88a (108686), Rat Ccdc88a (305605), chicken CCDC88A (421210), domestic cat CCDC88A (101096803), cow CCDC88A (533248), Horse CCDC88A (100052471), dog CCDC88A (481375), domestic guinea pig Ccdc88a (100714383), naked mole-rat Ccdc88a (101708183) ...More
UniProtKB ID:
Gene ID:
- Human(55704) Summary: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Mouse(108686) coiled coil domain containing 88A
- Rat(305605) coiled coil domain containing 88A
- chicken(421210) coiled-coil domain containing 88A
- domestic cat(101096803) coiled-coil domain containing 88A
- cow(533248) coiled-coil domain containing 88A
- Horse(100052471) coiled-coil domain containing 88A
- dog(481375) coiled-coil domain containing 88A
- domestic guinea pig(100714383) coiled-coil domain containing 88A
- naked mole-rat(101708183) coiled-coil domain containing 88A
- sheep(101122010) coiled-coil domain containing 88A
- Domestic Rabbit(100346692) coiled-coil domain containing 88A
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-Girdin (pSer1417) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
Anti-Girdin Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, monkey, rat
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Girdin Antibody, CT, clone 10E6.1, clone 10E6.1, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Girdin, coiled-coil region Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, monkey, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CCDC88A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry