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Merck

AXL

AXL receptor tyrosine kinase

Synonyms:
JTK11, UFO
Species:
UniProtKB ID:
Gene ID:
  • Human(558) Summary: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(26362) AXL receptor tyrosine kinase
  • Rat(308444) Axl receptor tyrosine kinase
  • Thale Cress(817802) AXR1-like protein
  • cow(516598) AXL receptor tyrosine kinase
  • Horse(100064907) AXL receptor tyrosine kinase
  • domestic cat(101086688) AXL receptor tyrosine kinase
  • dog(484490) AXL receptor tyrosine kinase
  • sheep(101102750) AXL receptor tyrosine kinase
  • domestic guinea pig(100729961) AXL receptor tyrosine kinase
  • naked mole-rat(101701026) AXL receptor tyrosine kinase

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Human Axl ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Phosphotyrosine AXL / Tyrosine-protein Kinase Receptor UFO ELISA Kit, ,
Species
human
Mouse Axl ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-AXL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-AXL antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-AXL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-AXL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-AXL (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, pig, rat
Application
western blot

Proteins

Product Number
Description
Species
Axl Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 473-end human Axl, for use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Axl,
Species
mouse
MISSION® esiRNA, targeting human AXL,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
Axltide, ,
Species
human