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Merck

ADRB2

adrenoceptor beta 2, surface

Synonyms:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Species:
UniProtKB ID:
Gene ID:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface

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Small Molecule - Agonist

Product Number
Description
Species
Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Metaproterenol hemisulfate salt, ,
Species
human
Metaproterenol sulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Albuterol sulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Pirbuterol acetate, VETRANAL®, analytical standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Species
human
Propranolol hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Timolol maleate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Propranolol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADRB2, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-Adrenoceptor β-2 Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor β2 (pSer346) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Species
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Species
human
Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADRB2,
Species
human
MISSION® esiRNA, targeting mouse Adrb2,
Species
mouse