- Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.
Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.
The Journal of organic chemistry (2007-01-16)
Fabrice Denes, Alejandro Perez-Luna, Fabrice Chemla
PMID17221954
ABSTRACT
Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction.