Antimicrobial effect of linalool and α-terpineol against periodontopathic and cariogenic bacteria.

Antimicrobial effect of linalool and α-terpineol against periodontopathic and cariogenic bacteria.

Anaerobe (2012-04-28)

Soon-Nang Park, Yun Kyong Lim, Marcelo Oliveira Freire, Eugene Cho, Dongchun Jin, Joong-Ki Kook

ABSTRACT

Linalool and α-terpineol exhibited strong antimicrobial activity against periodontopathic and cariogenic bacteria. However, their concentration should be kept below 0.4 mg/ml if they are to be used as components of toothpaste or gargling solution. Moreover, other compounds with antimicrobial activity against periodontopathic and cariogenic bacteria should be used in combination.

MATERIALS

Product Number

Brand

Product Description

W304506

Sigma-Aldrich

Terpineol, mixture of isomers, 96%, FG

83073

Supelco

(+)-α-Terpineol, analytical standard

432628

Sigma-Aldrich

α-Terpineol, 90%, technical grade

W304522

Sigma-Aldrich

(−)−α-Terpineol, natural, ≥96%, FCC, FG