SAB4500194

Anti-ERD22 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): ELP-1, ER lumen protein retaining receptor 2, ERD2-like protein 1, KDEL endoplasmic reticulum protein retention receptor 2, KDEL receptor 2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 24 kDa
• species reactivity: mouse, human, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI accession no.: P33947
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ERD22(11014)

Description

General description

Anti-ERD22 Antibody detects endogenous levels of total ERD22 protein.

ERD22 (ER lumen protein retaining receptor 2) is also known as KDEL (endoplasmic reticulum protein retention receptor 1). It codes for a a 26kDa integral membrane protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human ERD22.

Immunogen Range: 81-130

Biochem/physiol Actions

ERD22 (ER lumen protein retaining receptor 2) is essential for retention. It is redistributed from the Golgi apparatus to the endoplasmic reticulum (ER) due to higher expression of KDEL (endoplasmic reticulum protein retention receptor 1) .Mutation of hERD2 changes the specificity of ligand and communicate directly with the retained proteins.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable