M5883

7-Methylguanosine 5′-diphosphate sodium salt

≥92.5%

• Synonym(s): 7-Methyl-gdp, m⁷GDP
• Empirical Formula (Hill Notation): C₁₁H₁₇N₅O₁₁P₂ · xNa⁺
• CAS Number: 104809-16-7
• Molecular Weight: 457.23 (free acid basis)
• MDL number: MFCD00057869
• UNSPSC Code: 41106305
• PubChem Substance ID: 329818024
• NACRES: NA.51

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Assay: ≥92.5%
• form: powder
• solubility: water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13
• InChI: 1S/C11H17N5O11P2.2Na/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22;;/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChI key: VSMXIKIFPKDZJA-IDIVVRGQSA-L

Description

General description

7-Methylguanosine 5′-diphosphate (m⁷GDP) is derived when the human decapping Dcp2 enzyme cleaves the cap of the deadenylated mRNAs during the 5′–3′ mRNA decay pathway.

Application

7-Methylguanosine 5′-diphosphate sodium salt has been used as a component of the elution buffer for the purification of 5’capped RNA.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves