VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
Synonyms:
NR1I1
Species:
Human VDR (7421), Mouse Vdr (22337), Rat Vdr (24873), chicken VDR (395988), dog VDR (486588), Horse VDR (100034072), domestic cat VDR (100316614), cow VDR (533656), sheep VDR (101107273), sheep VDR (100294603) ...More
UniProtKB ID:
Gene ID:
- Human(7421) Summary: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
- Mouse(22337) vitamin D receptor
- Rat(24873) vitamin D (1,25- dihydroxyvitamin D3) receptor
- chicken(395988) vitamin D (1,25- dihydroxyvitamin D3) receptor
- dog(486588) vitamin D (1,25- dihydroxyvitamin D3) receptor
- Horse(100034072) vitamin D (1,25- dihydroxyvitamin D3) receptor
- domestic cat(100316614) vitamin D (1,25- dihydroxyvitamin D3) receptor
- cow(533656) vitamin D (1,25- dihydroxyvitamin D3) receptor
- sheep(101107273) vitamin D (1,25- dihydroxyvitamin D3) receptor
- sheep(100294603) vitamin D (1,25- dihydroxyvitamin D3) receptor
- naked mole-rat(101710294) vitamin D (1,25- dihydroxyvitamin D3) receptor
- domestic guinea pig(100734655) vitamin D (1,25- dihydroxyvitamin D3) receptor
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Small Molecule - Agonist
Product Number
Description
Species
Alfacalcidol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Cholecalciferol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Ergocalciferol (Vitamin D2), Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Cholecalciferol (Vitamin D3), Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Vitamin D Receptor antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-VDR antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-VDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-phospho-Vitamin D Receptor (pSer208) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Vitamin D Receptor (Ab-1) Rat mAb (9A7γE10.4), liquid, clone 9A7γE10.4, Calbiochem®,
Species Reactivity
amphibian, chicken, hamster, human, mouse, porcine, rat
Application
Proteins
Product Number
Description
Species
Vitamin D Receptor human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Species
human
Vitamin D receptor (118-427), His tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
PrEST Antigen VDR, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
esiRNA
Product Number
Description
Species