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Merck

TAX1BP1

Tax1 (human T-cell leukemia virus type I) binding protein 1

Synonyms:
CALCOCO3, T6BP, TXBP151
Species:
Human TAX1BP1 (8887), Mouse Tax1bp1 (52440), Rat Tax1bp1 (246244), chicken TAX1BP1 (395490), dog TAX1BP1 (475264), Horse TAX1BP1 (100054756), domestic cat TAX1BP1 (101080772), cow TAX1BP1 (535589), sheep TAX1BP1 (101103972), domestic guinea pig Tax1bp1 (100732558)
UniProtKB ID:
Q86VP1, B4DKU7, E7ENV2, O60398, O95770, Q13311, Q9BQG5, Q9UI88
Gene ID:
  • Human(8887) Summary: This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
  • Mouse(52440) Tax1 (human T cell leukemia virus type I) binding protein 1
  • Rat(246244) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • chicken(395490) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • dog(475264) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • Horse(100054756) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • domestic cat(101080772) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • cow(535589) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • sheep(101103972) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • domestic guinea pig(100732558) Tax1 (human T-cell leukemia virus type I) binding protein 1
  • naked mole-rat(101704862) Tax1 (human T-cell leukemia virus type I) binding protein 1

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