SP3
Sp3 transcription factor
Synonyms:
SPR2
Species:
Human SP3 (6670), Mouse Sp3 (20687), Rat Sp3 (367846), chicken SP3 (395302), Horse SP3 (100064317), domestic cat SP3 (101090127), dog SP3 (488405), domestic guinea pig Sp3 (100729306), cow SP3 (540766), sheep SP3 (101106411)
UniProtKB ID:
Gene ID:
- Human(6670) Summary: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010]
- Mouse(20687) trans-acting transcription factor 3
- Rat(367846) Sp3 transcription factor
- chicken(395302) Sp3 transcription factor
- Horse(100064317) Sp3 transcription factor
- domestic cat(101090127) Sp3 transcription factor
- dog(488405) Sp3 transcription factor
- domestic guinea pig(100729306) Sp3 transcription factor
- cow(540766) Sp3 transcription factor
- sheep(101106411) Sp3 transcription factor
- sheep(100303457) Sp3 transcription factor
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