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Merck

SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

Synonyms:
OAT4L, RST, URAT1
Species:
UniProtKB ID:
Gene ID:
  • Human(116085) Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(20521) solute carrier family 22 (organic anion/cation transporter), member 12
  • Rat(365398) solute carrier family 22 (organic anion/urate transporter), member 12
  • Horse(100055832) solute carrier family 22 (organic anion/urate transporter), member 12
  • dog(483761) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic cat(101100592) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic guinea pig(100721051) solute carrier family 22 (organic anion/urate transporter), member 12
  • naked mole-rat(101714998) solute carrier family 22 (organic anion/urate transporter), member 12
  • cow(526067) solute carrier family 22 (organic anion/urate transporter), member 12
  • sheep(101117630) solute carrier family 22 (organic anion/urate transporter), member 12

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SLC22A12 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-SLC22A12 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Sulfinpyrazone, European Pharmacopoeia (EP) Reference Standard,
Species
human
Benzbromarone, European Pharmacopoeia (EP) Reference Standard,
Species
human
Lesinurad, ≥98% (HPLC),
Species
human
(±)-Sulfinpyrazone, analytical standard,
Species
human
Benzbromarone, analytical standard,
Species
human