SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
Synonyms:
ASBT, IBAT, ISBT, NTCP2, PBAM
Species:
Human SLC10A2 (6555), Mouse Slc10a2 (20494), Rat Slc10a2 (29500), Zebrafish slc10a2 (393329), domestic cat SLC10A2 (101083393), dog SLC10A2 (403448), chicken SLC10A2 (428018), cow SLC10A2 (525823), sheep SLC10A2 (101114965), domestic guinea pig Slc10a2 (100733636) ...More
UniProtKB ID:
Gene ID:
- Human(6555) Summary: This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
- Mouse(20494) solute carrier family 10, member 2
- Rat(29500) solute carrier family 10 (sodium/bile acid cotransporter), member 2
- Zebrafish(393329) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- domestic cat(101083393) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- dog(403448) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- chicken(428018) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- cow(525823) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- sheep(101114965) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- domestic guinea pig(100733636) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- naked mole-rat(101696557) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
- Domestic Rabbit(100009550) solute carrier family 10 (sodium/bile acid cotransporter family), member 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SLC10A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, rat
Application
western blot