RBM8A
RNA binding motif protein 8A
Synonyms:
BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, RBM8B, TAR, Y14, ZNRP, ZRNP1
Species:
Human RBM8A (9939), Mouse Rbm8a (60365), Rat Rbm8a (295284), Zebrafish rbm8a (503767), domestic cat RBM8A (101098563), Horse RBM8A (100034052), dog RBM8A (475827), domestic guinea pig Rbm8a (100731698), naked mole-rat Rbm8a (101702668), cow RBM8A (518045)
UniProtKB ID:
Gene ID:
- Human(9939) Summary: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
- Mouse(60365) RNA binding motif protein 8a
- Rat(295284) RNA binding motif protein 8A
- Zebrafish(503767) RNA binding motif protein 8A
- domestic cat(101098563) RNA binding motif protein 8A
- Horse(100034052) RNA binding motif protein 8A
- dog(475827) RNA binding motif protein 8A
- domestic guinea pig(100731698) RNA binding motif protein 8A
- naked mole-rat(101702668) RNA binding motif protein 8A
- cow(518045) RNA binding motif protein 8A
- sheep(101117890) RNA binding motif protein 8A
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