PTPRN
protein tyrosine phosphatase, receptor type, N
Synonyms:
IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Species:
Human PTPRN (5798), Mouse Ptprn (19275), Rat Ptprn (116660), domestic cat PTPRN (101100657), dog PTPRN (478921), cow PTPRN (286810), sheep PTPRN (101113312), Domestic Rabbit PTPRN (100355368), naked mole-rat Ptprn (101718650), domestic guinea pig Ptprn (100733759)
UniProtKB ID:
Gene ID:
- Human(5798) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
- Mouse(19275) protein tyrosine phosphatase, receptor type, N
- Rat(116660) protein tyrosine phosphatase, receptor type, N
- domestic cat(101100657) protein tyrosine phosphatase, receptor type, N
- dog(478921) protein tyrosine phosphatase, receptor type, N
- cow(286810) protein tyrosine phosphatase, receptor type, N
- sheep(101113312) protein tyrosine phosphatase, receptor type, N
- Domestic Rabbit(100355368) protein tyrosine phosphatase, receptor type, N
- naked mole-rat(101718650) protein tyrosine phosphatase, receptor type, N
- domestic guinea pig(100733759) protein tyrosine phosphatase, receptor type, N
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPRN antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human, mouse, rabbit, rat
Application
western blot
Anti-IA2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species