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Merck

ORC6

origin recognition complex, subunit 6

Synonyms:
ORC6L
Species:
Human ORC6 (23594), Mouse Orc6 (56452), Rat Orc6 (291927), fruit fly Orc6 (36017), Thale Cress ORC6 (839227), cow ORC6 (515476), Zebrafish orc6 (324256), domestic cat ORC6 (101087628), dog ORC6 (482492), chicken ORC6 (415749) ...More
UniProtKB ID:
Q9Y5N6, B3KN89
Gene ID:
  • Human(23594) Summary: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]
  • Mouse(56452) origin recognition complex, subunit 6
  • Rat(291927) origin recognition complex, subunit 6
  • fruit fly(36017) Origin recognition complex subunit 6
  • Thale Cress(839227) origin recognition complex subunit 6
  • cow(515476) origin recognition complex, subunit 6
  • Zebrafish(324256) origin recognition complex, subunit 6
  • domestic cat(101087628) origin recognition complex, subunit 6
  • dog(482492) origin recognition complex, subunit 6
  • chicken(415749) origin recognition complex, subunit 6
  • sheep(101109557) origin recognition complex, subunit 6
  • naked mole-rat(101697513) origin recognition complex, subunit 6
  • domestic guinea pig(100728517) origin recognition complex, subunit 6

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Antibodies

Product Number
Description
Species Reactivity
Application
05-938
Anti-ORC6 Antibody, clone 3A4, clone 3A4, Upstate®, from rat,
Species Reactivity
human
Application
ChIP
western blot