NR3C2

nuclear receptor subfamily 3, group C, member 2

Synonyms:

MCR, MLR, MR, NR3C2VIT

Species:

UniProtKB ID:

Gene ID:

Human(4306) Summary: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Mouse(110784) nuclear receptor subfamily 3, group C, member 2
Rat(25672) nuclear receptor subfamily 3, group C, member 2
Zebrafish(562171) nuclear receptor subfamily 3, group C, member 2
dog(475461) nuclear receptor subfamily 3, group C, member 2
cow(280861) nuclear receptor subfamily 3, group C, member 2
cow(537614) nuclear receptor subfamily 3, group C, member 2
Horse(100062570) nuclear receptor subfamily 3, group C, member 2
domestic cat(101081977) nuclear receptor subfamily 3, group C, member 2
chicken(374131) nuclear receptor subfamily 3, group C, member 2
sheep(101107046) nuclear receptor subfamily 3, group C, member 2
domestic guinea pig(100735309) nuclear receptor subfamily 3, group C, member 2

siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.