MECOM
MDS1 and EVI1 complex locus
Synonyms:
AML1-EVI-1, EVI1, MDS1, MDS1-EVI1, PRDM3
Species:
Human MECOM (2122), Mouse Mecom (14013), Rat Mecom (294924), Zebrafish mecom (497407), cow MECOM (532209), dog MECOM (488148), Horse MECOM (100057450), domestic cat MECOM (101088775), chicken MECOM (424997), sheep MECOM (101121055) ...More
UniProtKB ID:
Gene ID:
- Human(2122) Summary: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- Mouse(14013) MDS1 and EVI1 complex locus
- Rat(294924) MDS1 and EVI1 complex locus
- Zebrafish(497407) MDS1 and EVI1 complex locus
- cow(532209) MDS1 and EVI1 complex locus
- dog(488148) MDS1 and EVI1 complex locus
- Horse(100057450) MDS1 and EVI1 complex locus
- domestic cat(101088775) MDS1 and EVI1 complex locus
- chicken(424997) MDS1 and EVI1 complex locus
- sheep(101121055) MDS1 and EVI1 complex locus
- naked mole-rat(101718355) MDS1 and EVI1 complex locus
- domestic guinea pig(100727638) MDS1 and EVI1 complex locus
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