GPX4
glutathione peroxidase 4
Synonyms:
GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx
Species:
Human GPX4 (2879), Mouse Gpx4 (625249), Rat Gpx4 (29328), Thale Cress GPX4 (819427), domestic cat GPX4 (101095956), chicken GPX4 (374056), cow GPX4 (286809), domestic guinea pig Gpx4 (100730119), naked mole-rat Gpx4 (101708875), Goat GPX4 (100860867)
UniProtKB ID:
Gene ID:
- Human(2879) Summary: Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008]
- Mouse(625249) glutathione peroxidase 4
- Rat(29328) glutathione peroxidase 4
- Thale Cress(819427) glutathione peroxidase 4
- domestic cat(101095956) glutathione peroxidase 4
- chicken(374056) glutathione peroxidase 4
- cow(286809) glutathione peroxidase 4
- domestic guinea pig(100730119) glutathione peroxidase 4
- naked mole-rat(101708875) glutathione peroxidase 4
- Goat(100860867) glutathione peroxidase 4
- sheep(101113149) glutathione peroxidase 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GPX4, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-GPX4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-GPX4 (Isoform A and C) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Glutathione Peroxidase 4 Antibody, clone Mab63-1, clone Mab63-1, from mouse, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
dot blot
electron microscopy
immunohistochemistry
immunoprecipitation (IP)
western blot
electron microscopy
immunohistochemistry
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species