GM2A
GM2 ganglioside activator
Synonyms:
GM2-AP, SAP-3
Species:
Human GM2A (2760), Mouse Gm2a (14667), Rat Gm2a (282838), sheep GM2A (101105496), domestic guinea pig Gm2a (100731438), naked mole-rat Gm2a (101706300), Zebrafish gm2a (550529), chicken GM2A (100857973), domestic cat GM2A (100174922), cow GM2A (504524) ...More
UniProtKB ID:
Gene ID:
- Human(2760) Summary: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
- Mouse(14667) GM2 ganglioside activator protein
- Rat(282838) GM2 ganglioside activator
- sheep(101105496) GM2 ganglioside activator
- domestic guinea pig(100731438) GM2 ganglioside activator
- naked mole-rat(101706300) GM2 ganglioside activator
- Zebrafish(550529) GM2 ganglioside activator
- chicken(100857973) GM2 ganglioside activator
- domestic cat(100174922) GM2 ganglioside activator
- cow(504524) GM2 ganglioside activator
- Horse(100034082) GM2 ganglioside activator
- dog(479324) GM2 ganglioside activator
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.