GLDC
glycine dehydrogenase (decarboxylating)
Synonyms:
GCE, GCSP, HYGN1
Species:
Human GLDC (2731), Mouse Gldc (104174), Rat Gldc (309312), Zebrafish gldc (321621), domestic cat GLDC (101100163), cow GLDC (507688), Horse GLDC (100060355), dog GLDC (481534), chicken GLDC (374222), sheep GLDC (101117476) ...More
UniProtKB ID:
Gene ID:
- Human(2731) Summary: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010]
- Mouse(104174) glycine decarboxylase
- Rat(309312) glycine dehydrogenase (decarboxylating)
- Zebrafish(321621) glycine dehydrogenase (decarboxylating)
- domestic cat(101100163) glycine dehydrogenase (decarboxylating)
- cow(507688) glycine dehydrogenase (decarboxylating)
- Horse(100060355) glycine dehydrogenase (decarboxylating)
- dog(481534) glycine dehydrogenase (decarboxylating)
- chicken(374222) glycine dehydrogenase (decarboxylating)
- sheep(101117476) glycine dehydrogenase (decarboxylating)
- Domestic Rabbit(100343694) glycine dehydrogenase (decarboxylating)
- domestic guinea pig(100714862) glycine dehydrogenase (decarboxylating)
- naked mole-rat(101725465) glycine dehydrogenase (decarboxylating)
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