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Merck

G3BP1

GTPase activating protein (SH3 domain) binding protein 1

Synonyms:
G3BP, HDH-VIII
Species:
Human G3BP1 (10146), Mouse G3bp1 (27041), Rat G3bp1 (171092), Zebrafish g3bp1 (335512), chicken G3BP1 (416265), domestic cat G3BP1 (101099615), cow G3BP1 (534214), dog G3BP1 (479322), sheep G3BP1 (101106523), domestic guinea pig G3bp1 (100725714)
UniProtKB ID:
Q13283
Gene ID:
  • Human(10146) Summary: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(27041) GTPase activating protein (SH3 domain) binding protein 1
  • Rat(171092) GTPase activating protein (SH3 domain) binding protein 1
  • Zebrafish(335512) GTPase activating protein (SH3 domain) binding protein 1
  • chicken(416265) GTPase activating protein (SH3 domain) binding protein 1
  • domestic cat(101099615) GTPase activating protein (SH3 domain) binding protein 1
  • cow(534214) GTPase activating protein (SH3 domain) binding protein 1
  • dog(479322) GTPase activating protein (SH3 domain) binding protein 1
  • sheep(101106523) GTPase activating protein (SH3 domain) binding protein 1
  • domestic guinea pig(100725714) GTPase activating protein (SH3 domain) binding protein 1
  • naked mole-rat(101696790) GTPase activating protein (SH3 domain) binding protein 1

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0010146M1
Monoclonal Anti-G3BP antibody produced in mouse, clone 2F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4300064
Anti-phospho-G3BP1 (pSer232) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
05-1938
Anti-G3BP1 Antibody, clone 14E5-G9, clone 14E5-G9, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot
ZRB1789
Anti-G3BP1 Antibody, clone 1B10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine
Application
immunocytochemistry
immunohistochemistry
western blot
PLA0231
Rabbit anti-G3BP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot