FH
fumarate hydratase
Synonyms:
HLRCC, LRCC, MCL, MCUL1
Species:
Human FH (2271), Mouse fh (14193), Rat Fh (24368), sheep FH (100302102), naked mole-rat Fh (101715373), domestic guinea pig Fh (100723287), Zebrafish fh (393938), Thale Cress FH (828013), chicken FH (420969), fruit fly fh (31845) ...More
UniProtKB ID:
Gene ID:
- Human(2271) Summary: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
- Mouse(14193) fetal hematoma
- Rat(24368) fumarate hydratase
- sheep(100302102) fumarate hydratase
- naked mole-rat(101715373) fumarate hydratase
- domestic guinea pig(100723287) fumarate hydratase
- Zebrafish(393938) fumarate hydratase
- Thale Cress(828013) frataxin
- chicken(420969) fumarate hydratase
- fruit fly(31845) frataxin homolog
- dog(480092) fumarate hydratase
- Horse(100060381) fumarate hydratase
- cow(520260) fumarate hydratase
- domestic cat(101096029) fumarate hydratase
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Custom Gene Products
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Kits
Product Number
Description
Species
Fumarase Activity Colorimetric Assay Kit, Sufficient for 100 Colorimetric tests,
Species
mouse, human, rat
Proteins
Product Number
Description
Species