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Merck

FGG

fibrinogen gamma chain

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2266) Summary: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(99571) fibrinogen gamma chain
  • Rat(24367) fibrinogen gamma chain
  • Zebrafish(406327) fibrinogen, gamma polypeptide
  • dog(475474) fibrinogen gamma chain
  • cow(280792) fibrinogen gamma chain
  • Horse(100147221) fibrinogen gamma chain
  • domestic cat(101092680) fibrinogen gamma chain
  • chicken(395837) fibrinogen gamma chain
  • Domestic Rabbit(100351591) fibrinogen gamma chain
  • domestic guinea pig(100720373) fibrinogen gamma chain
  • naked mole-rat(101696987) fibrinogen gamma chain

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FGG antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-FGG antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-FGG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Monoclonal Anti-FGG antibody produced in mouse, clone 1E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-Fibrinogen antibody produced in goat, whole antiserum,
Species Reactivity
human
Application
ELISA
quantitative precipitin assay

Proteins

Product Number
Description
Species
PrEST Antigen FGG, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
Fibrinogen from bovine plasma, Type I-S, 65-85% protein (≥75% of protein is clottable),
Species
cow
Fibrinogen from rat plasma, 60-80% protein (≥60% of protein is clottable),
Species
rat
Fibrinogen from human plasma, 50-70% protein (≥80% of protein is clottable),
Species
human
Fibrin from human plasma, insoluble powder,
Species
human