ESR1
estrogen receptor 1
Synonyms:
ER, ESR, ESRA, ESTRR, Era, NR3A1
Species:
Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), Goat ESR1 (100860768), sheep ESR1 (443228), domestic guinea pig Esr1 (100713276), Zebrafish esr1 (259252), dog ESR1 (403640), cow ESR1 (407238), Horse ESR1 (791249) ...More
UniProtKB ID:
Gene ID:
- Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
- Mouse(13982) estrogen receptor 1 (alpha)
- Rat(24890) estrogen receptor 1
- Goat(100860768) estrogen receptor 1
- sheep(443228) estrogen receptor 1
- domestic guinea pig(100713276) estrogen receptor 1
- Zebrafish(259252) estrogen receptor 1
- dog(403640) estrogen receptor 1
- cow(407238) estrogen receptor 1
- Horse(791249) estrogen receptor 1
- domestic cat(552888) estrogen receptor 1
- chicken(396099) estrogen receptor 1
- Thale Cress(837856) ethylene-responsive transcription factor ESR1
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Small Molecule - Activator
Product Number
Description
Species
Small Molecule - Agonist
Product Number
Description
Species
17β-Estradiol solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Ethinylestradiol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Tamoxifen, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
Tamoxifen citrate for performance test, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-Estrogen Receptor-α (pTyr537) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Rabbit anti-Estrogen Receptor Alpha Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
western blot
Anti-ESR1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-phospho-Estrogen Receptor-α (pSer167) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ESR1 (Ab-106) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Product Number
Description
Species
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species
Proteins
Product Number
Description
Species
Estrogen Receptor-α human, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species