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Merck

DNM2

dynamin 2

Synonyms:
CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
Species:
Human DNM2 (1785), Mouse Dnm2 (13430), Rat Dnm2 (25751), dog DNM2 (484949), cow DNM2 (511691), domestic cat DNM2 (101100788), sheep DNM2 (101115027), domestic guinea pig Dnm2 (100717689), naked mole-rat Dnm2 (101696596)
UniProtKB ID:
P50570, A8K1B6, E7EV30, E9PEQ4, K7ESI9, Q5I0Y0, Q7Z5S3, Q9UPH4
Gene ID:
  • Human(1785) Summary: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
  • Mouse(13430) dynamin 2
  • Rat(25751) dynamin 2
  • dog(484949) dynamin 2
  • cow(511691) dynamin 2
  • domestic cat(101100788) dynamin 2
  • sheep(101115027) dynamin 2
  • domestic guinea pig(100717689) dynamin 2
  • naked mole-rat(101696596) dynamin 2

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4200661
Monoclonal Anti-Dynamin 2 (DNM2) antibody produced in mouse, clone DYN2-11, purified from hybridoma cell culture,
Species Reactivity
Application
immunofluorescence
immunoprecipitation (IP)
western blot
P2122
Anti-phospho-Dynamin (pSer778) antibody produced in sheep, affinity isolated antibody, aqueous glycerol suspension,
Species Reactivity
human, mouse, rat
Application
western blot
P1997
Anti-phospho-Dynamin (pSer774) antibody produced in sheep, affinity isolated antibody, aqueous glycerol suspension,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot