DAXX
death-domain associated protein
Synonyms:
BING2, DAP6, EAP1
Species:
Human DAXX (1616), Mouse Daxx (13163), Rat Daxx (140926), naked mole-rat Daxx (101717412), domestic guinea pig Daxx (100730008), sheep DAXX (100505403), Zebrafish daxx (561006), dog DAXX (474873), cow DAXX (504336), domestic cat DAXX (101089265)
UniProtKB ID:
Gene ID:
- Human(1616) Summary: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
- Mouse(13163) Fas death domain-associated protein
- Rat(140926) death-domain associated protein
- naked mole-rat(101717412) death-domain associated protein
- domestic guinea pig(100730008) death-domain associated protein
- sheep(100505403) death-domain associated protein
- Zebrafish(561006) death-associated protein 6
- dog(474873) death-domain associated protein
- cow(504336) death-domain associated protein
- domestic cat(101089265) death-domain associated protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-DAXX antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Daxx antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-phospho-Daxx (pSer668) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Rabbit anti-DAXX Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
western blot