CYP26B1

cytochrome P450, family 26, subfamily B, polypeptide 1

Synonyms:

CYP26A2, P450RAI-2, P450RAI2, RHFCA

Species:

UniProtKB ID:

Gene ID:

Human(56603) Summary: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Mouse(232174) cytochrome P450, family 26, subfamily b, polypeptide 1
Rat(312495) cytochrome P450, family 26, subfamily b, polypeptide 1
Zebrafish(324188) cytochrome P450, family 26, subfamily b, polypeptide 1
chicken(428809) cytochrome P450, family 26, subfamily B, polypeptide 1
cow(540868) cytochrome P450, family 26, subfamily B, polypeptide 1
dog(483120) cytochrome P450, family 26, subfamily B, polypeptide 1

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Product Number

Description

Species Reactivity

Application

Monoclonal Anti-CYP26B1 antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,

Species Reactivity

human

Application

ELISA
immunofluorescence
western blot