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Merck

CST3

cystatin C

Synonyms:
ARMD11
Species:
Human CST3 (1471), Mouse Cst3 (13010), Rat Cst3 (25307), Zebrafish cst3 (791878), chicken CST3 (396497), cow CST3 (281102), domestic cat CST3 (100462660), sheep CST3 (101104079), Domestic Rabbit CST3 (100009450)
UniProtKB ID:
P01034, B2R5J9, D3DW42, Q6FGW9
Gene ID:
  • Human(1471) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq, Jul 2008]
  • Mouse(13010) cystatin C
  • Rat(25307) cystatin C
  • Zebrafish(791878) cystatin C (amyloid angiopathy and cerebral hemorrhage)
  • chicken(396497) cystatin C
  • cow(281102) cystatin C
  • domestic cat(100462660) cystatin C
  • sheep(101104079) cystatin C
  • Domestic Rabbit(100009450) cystatin C

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ELISA

Product Number
Description
Species
RAB0105
Human Cystatin C ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
RAB0106
Mouse Cystatin C ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
RAB0890
Rat Cst3 / Cystatin-C ELISA Kit, ,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2501239
Anti-CST3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot