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Merck

CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

Synonyms:
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Species:
UniProtKB ID:
Gene ID:
  • Human(1140) Summary: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(11443) cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
  • Rat(24261) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Zebrafish(100006941) cholinergic receptor, nicotinic, beta 1 (muscle)
  • cow(282179) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Horse(100072990) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic cat(101097433) cholinergic receptor, nicotinic, beta 1 (muscle)
  • dog(489473) cholinergic receptor, nicotinic, beta 1 (muscle)
  • sheep(101121614) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Domestic Rabbit(100357163) cholinergic receptor, nicotinic, beta 1 (muscle)
  • naked mole-rat(101723288) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic guinea pig(100714100) cholinergic receptor, nicotinic, beta 1 (muscle)

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Small Molecule - Agonist

Product Number
Description
Species
DBO-83, solid,
Species
human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat
Decamethonium bromide, crystalline,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
Tubocurarine hydrochloride pentahydrate, ≥97%,
Species
human
Pancuronium bromide, ,
Species
human
Tubocurarine chloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Pancuronium bromide, European Pharmacopoeia (EP) Reference Standard,
Species
human
Atracurium for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CHRNB1 antibody produced in mouse, clone 4G4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Small Molecule - Blocker

Product Number
Description
Species
Hexamethonium bromide, ,
Species
human
Hexamethonium chloride, solid (hygroscopic),
Species
human
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Kynurenic acid, ≥98%,
Species
rat, human