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Merck

CFL1

cofilin 1 (non-muscle)

Synonyms:
CFL
Species:
UniProtKB ID:
Gene ID:
  • Human(1072) Summary: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
  • Mouse(12631) cofilin 1, non-muscle
  • Rat(29271) cofilin 1, non-muscle
  • Zebrafish(406738) cofilin 1 (non-muscle)
  • cow(534553) cofilin 1 (non-muscle)
  • dog(476022) cofilin 1 (non-muscle)
  • domestic cat(101100251) cofilin 1 (non-muscle)
  • naked mole-rat(101713836) cofilin 1 (non-muscle)
  • domestic guinea pig(100732287) cofilin 1 (non-muscle)
  • sheep(494432) cofilin 1 (non-muscle)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CFL1 antibody produced in mouse, clone 1A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-phospho-Cofilin (pSer3) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-phospho-CFL1 (pSer3) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-Cofilin 1 antibody produced in mouse, clone GT567, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-Cofilin (pSer3) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, pig, rat
Application
western blot

Proteins

Product Number
Description
Species
Cofilin 1 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human