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Merck

CD8A

CD8a molecule

Synonyms:
CD8, Leu2, MAL, p32
Species:
UniProtKB ID:
Gene ID:
  • Human(925) Summary: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(12525) CD8 antigen, alpha chain
  • Rat(24930) CD8a molecule
  • Zebrafish(677754) CD8 antigen, alpha polypeptide
  • chicken(428800) CD8a molecule
  • cow(281060) CD8a molecule
  • domestic cat(493799) CD8a molecule
  • dog(403157) CD8a molecule
  • chicken(403158) CD8a molecule
  • naked mole-rat(101720748) CD8a molecule
  • domestic guinea pig(100379570) CD8 antigen, alpha chain
  • sheep(101103464) CD8a molecule

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CD8a (human), PE, clone RPA-T8 Antibody, clone RPA-T8, from mouse, PE,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD8a antibody produced in mouse, clone OX-8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
rat
Application
FUNC
flow cytometry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CD8a Antibody, clone 1B19, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-CD8a Antibody, clone YTS 169.4, clone YTS 169.4, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunodepletion

immunohistochemistry
Milli-Mark Anti-CD8 -FITC Antibody, clone DK25, clone DK25, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry