BIRC7
baculoviral IAP repeat containing 7
Synonyms:
KIAP, LIVIN, ML-IAP, MLIAP, RNF50
Species:
Human BIRC7 (79444), Mouse Birc7 (329581), Rat Birc7 (296468), Zebrafish birc7 (100073331), cow BIRC7 (514508), domestic cat BIRC7 (101080371), dog BIRC7 (485969), chicken BIRC7 (419239), sheep BIRC7 (101110435), domestic guinea pig Birc7 (100717708)
UniProtKB ID:
Gene ID:
- Human(79444) Summary: The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq, Jul 2008]
- Mouse(329581) baculoviral IAP repeat-containing 7 (livin)
- Rat(296468) baculoviral IAP repeat-containing 7
- Zebrafish(100073331) baculoviral IAP repeat-containing 7
- cow(514508) baculoviral IAP repeat containing 7
- domestic cat(101080371) baculoviral IAP repeat containing 7
- dog(485969) baculoviral IAP repeat containing 7
- chicken(419239) baculoviral IAP repeat containing 7
- sheep(101110435) baculoviral IAP repeat containing 7
- domestic guinea pig(100717708) baculoviral IAP repeat containing 7
- naked mole-rat(101709798) baculoviral IAP repeat containing 7
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