ARRB2
arrestin, beta 2
Synonyms:
ARB2, ARR2, BARR2
Species:
Human ARRB2 (409), Mouse Arrb2 (216869), Rat Arrb2 (25388), domestic guinea pig Arrb2 (100716149), naked mole-rat Arrb2 (101709908), sheep ARRB2 (101112493), Domestic Rabbit ARRB2 (100341204), Horse ARRB2 (100072892), domestic cat ARRB2 (101093558), dog ARRB2 (607262)
UniProtKB ID:
Gene ID:
- Human(409) Summary: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
- Mouse(216869) arrestin, beta 2
- Rat(25388) arrestin, beta 2
- domestic guinea pig(100716149) arrestin, beta 2
- naked mole-rat(101709908) arrestin, beta 2
- sheep(101112493) arrestin, beta 2
- Domestic Rabbit(100341204) arrestin, beta 2
- Horse(100072892) arrestin, beta 2
- domestic cat(101093558) arrestin, beta 2
- dog(607262) arrestin, beta 2
- cow(281638) arrestin, beta 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ARRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-ARRB2 antibody produced in mouse, clone 3G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-Arrestin β2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
PrEST Antigen ARRB2, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
Species
human