Intensified upstream bioprocesses are being developed to increase productivity while reducing footprint, costs, and timelines for manufacturing. The higher cell densities generated by intensification result in increased gassing and mixing requirements, to ensure a homogeneous cell culture environment with effective oxygenation and CO2 removal at all scales. The new Mobius® iFlex bioreactor was developed with an expanded design space, providing flexibility for a variety of bioprocesses. Impeller and motor designs reach up to 100 W/m3 with < 35 second mixing time while maintaining tip speeds under 2.2 m/s and innovative spargers achieve kLa of > 50 hr-1.
In this webinar, you will learn how our new single-use bioreactor family can help you:
- Fulfill any process strategy, be it batch, fed-batch, or perfusion
- Facilitate scalability of your upstream process
- Utilize the flexible design to reduce production costs
Speakers
Samantha Whitney
Merck
Applications Engineer
Samantha Whitney is an applications engineer within Merck's single-use and integrated systems bioprocessing R&D team. Since joining the company in 2021, she has contributed to generating performance and application testing data for upgraded intensified bioreactor designs. Prior to joining our company, Samantha worked as a research scientist in the small molecule pharmaceutical industry. She earned a B.S. in chemical engineering at the University of Massachusetts and an M.S. in engineering management at Tufts University.
Kristen Der
Merck
Associate Product Manager
Kristen is an associate product manager in Merck's Mobius iFlex team. She has recently taken on the management of the Mobius 3L Bioreactor and CRS. She has been with the organization for 3 years; prior to moving over to the single-use and integrated systems marketing team, she worked in technical service, supporting the science and lab solutions portfolios. She is a strong customer advocate and passionate about fostering a culture of diversity, collaboration, and teamwork. Kristen holds a B.S. in physiology and neurobiology from the University of Connecticut.
Pharma and biopharma manufacturing
- Pharma and biopharma manufacturing
Duration:1h
Language:English
Session 1:presented October 19, 2023
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