Skip to Content
Merck

High glucose stimulates expression of aldosterone synthase (

FEBS open bio (2017-09-15)
Hiroki Shimada, Naotaka Kogure, Erika Noro, Masataka Kudo, Kaori Sugawara, Ikuko Sato, Kyoko Shimizu, Makoto Kobayashi, Dai Suzuki, Rehana Parvin, Takako Saito-Ito, Akira Uruno, Akiko Saito-Hakoda, William E Rainey, Sadayoshi Ito, Atsushi Yokoyama, Akira Sugawara
ABSTRACT

Aldosterone synthase is the key rate-limiting enzyme in adrenal aldosterone production, and induction of its gene (

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Olmesartan, ≥98% (HPLC)
Sigma-Aldrich
L-(−)-Glucose, ≥99%
Sigma-Aldrich
Efonidipine hydrochloride monoethanolate, ≥98% (HPLC)
Sigma-Aldrich
Aldosterone, ≥95% (HPLC)
Sigma-Aldrich
MISSION® esiRNA, targeting human NR4A2