sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

GF46466860

Nickel, foil, 10mm disks, thickness 0.01mm, 99.95%

GF90338508

Nickel, foil, 4mm disks, thickness 0.03mm, 99.9%

GF57196569

Nickel, wire reel, 100m, diameter 0.25mm, annealed, 99%

GF58401660

Nickel, wire reel, 0.1m, diameter 1.0mm, as drawn, 99.99+%

GF01408711

Nickel, foil, 2m coil, thickness 0.15mm, coil width 12mm, annealed, 99%

GF47006243

Nickel, foil, 10mm disks, thickness 0.025mm, as rolled, 100%

GF58446580

Nickel, foil, 10m coil, thickness 0.3mm, coil width 1mm, as rolled, 99%

GF83472329

Nickel, wire reel, 10m, diameter 0.05mm, as drawn, 99.99+%

GF27854196

Nickel, foil, 50x50mm, thickness 1.6mm, 99%

GF34426470

Nickel, tube, 500mm, outside diameter 5.9mm, inside diameter 5.65mm, wall thickness 0.125mm, hard, 99.5%

GF84616207

Nickel, foil, 10mm disks, thickness 0.008mm, 99.95%

GF04087076

Nickel, wire reel, 10m, diameter 0.25mm, as drawn, 99%

GF86231729

Nickel, foil, 4mm disks, thickness 0.05mm, as rolled, 99.99+%

GF16048874

Nickel, microfoil, disks, 10mm, thinness 0.25μm, specific density 222.55μg/cm², permanent mylar 3.5μm support, 99.99+%

GF60595061

Nickel, wire reel, 100m, diameter 0.25mm, as drawn, 99%

GF27664836

Nickel, foil, 4mm disks, thickness 0.008mm, 99.95%

GF54355147

Nickel, wire reel, 0.2m, diameter 0.4mm, as drawn, 99.99+%

GF70648915

Nickel, foil, 2m coil, thickness 0.1mm, annealed, 99%

GF67542194

Nickel, foil, 10mm disks, thickness 0.0025mm, 99.95%

GF68422574

Nickel, foil, 300x300mm, thickness 2.0mm, annealed, 99%

GF91494355

Nickel, foil, 25x25mm, thickness 0.25mm, annealed, 99.98%