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  • [Interaction of pipolfen and suprastin with human serum albumin depending on the pH of the medium and its calcium ion content].

[Interaction of pipolfen and suprastin with human serum albumin depending on the pH of the medium and its calcium ion content].

Farmakologiia i toksikologiia (1983-11-01)
K I Bender, A N Lutsevich
ABSTRACT

Experiments made with the use of equilibrium dialysis and differential spectrophotometry have shown that pipolfen and difenhydramine interact actively with human serum albumin at pH 6.8-7.4. Calcium ions have been demonstrated to activate the interaction of pipolphen and diphenhydramine with albumin.

MATERIALS
Product Number
Brand
Product Description

Supelco
Chloropyramine hydrochloride, analytical standard, for drug analysis