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  • Correlations of Fat Content in Human Milk with Fat Droplet Size and Phospholipid Species.

Correlations of Fat Content in Human Milk with Fat Droplet Size and Phospholipid Species.

Molecules (Basel, Switzerland) (2021-04-04)
Beibei Duan, Eun-Sik Hong, Jung-Ah Shin, Yan Qin, Jeung-Hee Lee, Chi-Woo Lee, Ki-Teak Lee
ABSTRACT

Fat globule size and phospholipid (PL) content in human milk (HM) were investigated. HM was classified into three groups depending on fat content (A < B < C). PL content (mg/100 g HM) was significantly higher in the C group (p < 0.05), indicating its positive relationship with HM fat content. When the PL content was normalized (mg/g fat), that of group A was significantly higher (p < 0.05) and fat droplet size in group C was slightly larger, suggesting that HM fat content is affected by fat droplet numbers to a larger extent than by fat droplet size. A correlation between PC and SM content in HM was observed regardless of fat content, while correlation between PE and either PC or SM increased in the order of C > B > A, hence the composition and content of PL species in HM varied according to its fat content.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
L-α-Lysophosphatidylcholine, egg yolk, ≥99.0% (TLC)
Sigma-Aldrich
Sphingomyelin, from chicken egg yolk, ≥98.0% (TLC)