E5008

[D-Ala²]-Leucine enkephalin

≥97% (HPLC), suitable for ligand binding assays

• Synonym(s): Tyr-D-Ala-Gly-Phe-Leu
• Empirical Formula (Hill Notation): C₂₉H₃₉N₅O₇
• CAS Number: 64963-01-5
• Molecular Weight: 569.65
• EC Number: 265-291-0
• MDL number: MFCD00076409
• UNSPSC Code: 12352209
• PubChem Substance ID: 24894597
• NACRES: NA.26

Properties

• product name: [D-Ala²]-Leucine enkephalin, ≥97% (HPLC)
• Quality Level: 200
• Assay: ≥97% (HPLC)
• form: powder
• technique(s): ligand binding assay: suitable
• color: white
• storage temp.: −20°C
• SMILES string: CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(C)NC(=O)C(N)Cc2ccc(O)cc2)C(O)=O
• InChI: 1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)
• InChI key: ZHUJMSMQIPIPTF-UHFFFAOYSA-N

Description

Amino Acid Sequence

Tyr-Ala-Gly-Phe-Leu

Biochem/physiol Actions

The Enkephalin amid peptide [D-Ala2]-Leucine enkephalin ((DADLE), a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.

Other Notes

Potent, long-acting Leu-enkephalin analog that is resistant to enzymatic degradation

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable