765112

Poly(L-lactide)

average M_n 10,000, PDI ≤1.1

• Synonym(s): PLA, PLLA, Polylactide, L-Lactide polymer, PLA, Poly(L-Lactic acid)
• Linear Formula: H(C₃H₄O₂)_nOCH₃
• UNSPSC Code: 12162002
• NACRES: NA.23

Properties

• form: solid
• optical activity: [α]22/D -150°, c = 0.5% in chloroform
• mol wt: average M_n 10,000
• degradation timeframe: >3 years
• transition temp: T_m 162-167 °C
• PDI: ≤1.1
• storage temp.: 2-8°C

Description

General description

Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.

Application

Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.

Features and Benefits

High initial strength, good strength retention and high amount of crystallinity, as much as 70%, which in turn is responsible for the very slow degradation rate.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable