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Merck

SNRNP200

small nuclear ribonucleoprotein 200kDa (U5)

Synonyms:
ASCC3L1, BRR2, HELIC2, RP33, U5-200KD
Species:
UniProtKB ID:
Gene ID:
  • Human(23020) Summary: Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]
  • Mouse(320632) small nuclear ribonucleoprotein 200 (U5)
  • Rat(296126) small nuclear ribonucleoprotein 200 (U5)
  • Zebrafish(799690) small nuclear ribonucleoprotein 200 (U5)
  • Horse(100051471) small nuclear ribonucleoprotein 200kDa (U5)
  • domestic cat(101091688) small nuclear ribonucleoprotein 200kDa (U5)
  • chicken(503574) small nuclear ribonucleoprotein 200kDa (U5)
  • dog(475742) small nuclear ribonucleoprotein 200kDa (U5)
  • naked mole-rat(101704077) small nuclear ribonucleoprotein 200kDa (U5)
  • domestic guinea pig(100729921) small nuclear ribonucleoprotein 200kDa (U5)
  • cow(510529) small nuclear ribonucleoprotein 200kDa (U5)
  • sheep(101113316) small nuclear ribonucleoprotein 200kDa (U5)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SNRNP200 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SNRNP200 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SNRNP200,
Species
human