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Merck

RBM8A

RNA binding motif protein 8A

Synonyms:
BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, RBM8B, TAR, Y14, ZNRP, ZRNP1
Species:
UniProtKB ID:
Gene ID:
  • Human(9939) Summary: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
  • Mouse(60365) RNA binding motif protein 8a
  • Rat(295284) RNA binding motif protein 8A
  • Zebrafish(503767) RNA binding motif protein 8A
  • domestic cat(101098563) RNA binding motif protein 8A
  • Horse(100034052) RNA binding motif protein 8A
  • dog(475827) RNA binding motif protein 8A
  • domestic guinea pig(100731698) RNA binding motif protein 8A
  • naked mole-rat(101702668) RNA binding motif protein 8A
  • cow(518045) RNA binding motif protein 8A
  • sheep(101117890) RNA binding motif protein 8A

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RBM8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Y14 Antibody, clone 4C4, clone 4C4, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Y14/RBM8A Antibody, clone 5K5E6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rbm8a,
Species
mouse
MISSION® esiRNA, targeting human RBM8A,
Species
human