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Merck

PREX1

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

Synonyms:
P-REX1
Species:
UniProtKB ID:
Gene ID:
  • Human(57580) Summary: The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]
  • Mouse(277360) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • Rat(311647) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • Zebrafish(570984) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • chicken(419210) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • dog(485917) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • domestic cat(101082811) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • Domestic Rabbit(100357266) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • naked mole-rat(101700961) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • domestic guinea pig(100732655) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • cow(527410) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
  • sheep(101115893) phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PREX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-PREX1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
ANTI-PREX1 (CENTER) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-P-Rex1 Antibody, clone 6F12, clone 6F12, from mouse,
Species Reactivity
human
Application
western blot
ANTI-PREX1(C-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PREX1,
Species
human