PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Synonyms:
ADE2, ADE2H1, AIRC, PAIS
Species:
Human PAICS (10606), Mouse Paics (67054), Rat Paics (140946), Zebrafish paics (321193), cow PAICS (404170), Horse PAICS (100058501), domestic cat PAICS (101084705), dog PAICS (475150), chicken PAICS (396534), sheep PAICS (101117419) ...More
UniProtKB ID:
Gene ID:
- Human(10606) Summary: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(67054) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
- Rat(140946) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- Zebrafish(321193) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- cow(404170) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- Horse(100058501) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- domestic cat(101084705) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- dog(475150) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- chicken(396534) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- sheep(101117419) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- naked mole-rat(101721606) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
- domestic guinea pig(100727779) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ADE2 Antibody/SAICAR synthetase, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, canine, chimpanzee, feline, human, mouse, porcine, rat, rhesus monkey
Application
western blot
Anti-PAICS antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit
Application
western blot
Anti-PAICS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-PAICS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot