CSF1R
colony stimulating factor 1 receptor
Synonyms:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Species:
Human CSF1R (1436), Mouse Csf1r (12978), Rat Csf1r (307403), chicken CSF1R (396406), dog CSF1R (489188), cow CSF1R (509418), Horse CSF1R (100060422), domestic cat CSF1R (493706), domestic guinea pig Csf1r (100726053), naked mole-rat Csf1r (101719513)
UniProtKB ID:
Gene ID:
- Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
- Mouse(12978) colony stimulating factor 1 receptor
- Rat(307403) colony stimulating factor 1 receptor
- chicken(396406) colony stimulating factor 1 receptor
- dog(489188) colony stimulating factor 1 receptor
- cow(509418) colony stimulating factor 1 receptor
- Horse(100060422) colony stimulating factor 1 receptor
- domestic cat(493706) colony stimulating factor 1 receptor
- domestic guinea pig(100726053) colony stimulating factor 1 receptor
- naked mole-rat(101719513) colony stimulating factor 1 receptor
- sheep(101109969) colony stimulating factor 1 receptor
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CSF-1R/CD115 Antibody, clone 1F6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-CSF1R antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL11653, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-CD115 (c-fms) Antibody (mouse), PE, clone AFS98, clone AFS98, 0.2 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
western blot
western blot
Anti-phospho-CSFR (pTyr708) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Small Molecule - Inhibitor
Product Number
Description
Species