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Merck

BAIAP2L1

BAI1-associated protein 2-like 1

Synonyms:
IRTKS
Species:
UniProtKB ID:
Gene ID:
  • Human(55971) Summary: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq, Oct 2009]
  • Mouse(66898) BAI1-associated protein 2-like 1
  • Rat(304282) BAI1-associated protein 2-like 1
  • chicken(416437) BAI1-associated protein 2-like 1
  • dog(479748) BAI1-associated protein 2-like 1
  • cow(615412) BAI1-associated protein 2-like 1
  • domestic cat(101098023) BAI1-associated protein 2-like 1
  • naked mole-rat(101719088) BAI1-associated protein 2-like 1
  • domestic guinea pig(100724572) BAI1-associated protein 2-like 1
  • sheep(101114328) BAI1-associated protein 2-like 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-BAIAP2L1 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-BAIAP2L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BAIAP2L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BAIAP2L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-BAIAP2L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BAIAP2L1,
Species
human
MISSION® esiRNA, targeting mouse Baiap2l1,
Species
mouse