Skip to Content
Merck

ABCB4

ATP-binding cassette, sub-family B (MDR/TAP), member 4

Synonyms:
ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Species:
Human ABCB4 (5244), Mouse Abcb4 (18670), Rat Abcb4 (24891), Zebrafish abcb4 (100136865), dog ABCB4 (482284), domestic cat ABCB4 (101100709), cow ABCB4 (100336913), cow ABCB4 (783154), cow ABCB4 (100336338), Thale Cress ABCB4 (819314) ...More
UniProtKB ID:
P21439, A0A2V7, A4D1D3, A4D1D4, A4D1D5, D6W5P3, D6W5P4, Q14813
Gene ID:
  • Human(5244) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
  • Mouse(18670) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • Rat(24891) ATP-binding cassette, subfamily B (MDR/TAP), member 4
  • Zebrafish(100136865) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • dog(482284) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • domestic cat(101100709) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • cow(100336913) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • cow(783154) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • cow(100336338) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • Thale Cress(819314) auxin efflux transmembrane transporter MDR4
  • naked mole-rat(101717251) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • domestic guinea pig(100722900) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • sheep(101122517) ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • Domestic Rabbit(100354947) ATP-binding cassette, sub-family B (MDR/TAP), member 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
HPA053288
Anti-ABCB4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
SAB2108082
Anti-ABCB4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rabbit, rat
Application
western blot
SAB2108349
Anti-ABCB4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, rat
Application
western blot
MAB4140
Anti-MDR3 Antibody, clone P3 II-26, culture supernatant, clone P3 II-26, Chemicon®,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
M7317
Monoclonal Anti-MDR3 P-Glycoprotein antibody produced in mouse, 250 μg/mL, clone P3II-26, tissue culture supernatant,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot