- Gli1 identifies osteogenic progenitors for bone formation and fracture repair.
Gli1 identifies osteogenic progenitors for bone formation and fracture repair.
Nature communications (2017-12-13)
Yu Shi, Guangxu He, Wen-Chih Lee, Jennifer A McKenzie, Matthew J Silva, Fanxin Long
PMID29230039
摘要
Bone formation in mammals requires continuous production of osteoblasts throughout life. A common molecular marker for all osteogenic mesenchymal progenitors has not been identified. Here, by lineage-tracing experiments in fetal or postnatal mice, we discover that Gli1