- Estradiol-ERβ2 signaling axis confers growth and migration of CRPC cells through TMPRSS2-ETV5 gene fusion.
Estradiol-ERβ2 signaling axis confers growth and migration of CRPC cells through TMPRSS2-ETV5 gene fusion.
Oncotarget (2016-08-17)
Hogyoung Kim, Amrita Datta, Sudha Talwar, Sarmad N Saleem, Debasis Mondal, Asim B Abdel-Mageed
PMID28968951
摘要
Estrogen receptor beta (ERβ) splice variants are implicated in prostate cancer (PC) progression; however their underlying mechanisms remain elusive. We report that non-canonical activation of estradiol (E